Hedgehog signaling promotes the formation of three dimensional cartilage matrices
Patent Number: 7,160,725
Date of First Priority Issue: Tuesday November 13th, 2001
Date Issued: Tuesday January 9th, 2007
Assignee: Curis, Inc. (Cambridge, MA)
Inventors: Warzecha; Joerg (Frankfurt, DE)
From Class: 3D Culture/Scaffold
Comments: No comments
It is known that hedgehog proteins are involved in pattern specification during embryogenesis. The possibility of modulating the hedgehog signalling pathway for regulation of stem cell activity was previously patented for hematopoietic stem cells, neural stem cells and pancreatic stem cells.
In the current patent, the use of hedgehog proteins are covered for induction of mesenchymal cell growth and spreading on three dimensional scaffolds. This patent is very useful for growing artificial organs ranging from heart valves to bladders.
View this patent on the USPTO website.
Added to StemCellPatents.com on Sunday January 14th, 2007
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