Methods of producing neurons

Patent Number: 7,186,557

The current patent teaches methods of inducing differentiation of various adult stem cells into neuronal-like cells through culture on a blood clot alone or in the presence of various other cells and/or growth factors. It is known that various components released during the blood clotting process are mitogenic to stem cells, compoenents such as PDGF and FGF-2.

This patent is useful for the induction of differentiation of bone marrow, adipose tissue, mesenchymal stem cells and several other stem cells sources for production of neurons in vitro for in vivo use. An alternative use of the current patent is the generation of artificial neurons for in vitro pharmacological testing.

View this patent on the USPTO website.