Compositions, systems and methods for treatment of defects in blood vessels

Patent Number: 7,201,918

Vascular aneurysms are thinning of blood vessel walls, which is usually associated with vessel trauma, non-specific degeneration, atherosclerosis, or infection. The term "aneurysm" comes from the Latin "aneurysma" which means "dilation". Aneurysms are hazardous because of the potential to burst. They are usually prevelant in the aorta or cerebral arteries.

The current patent provides methods of treating blood vessel defects, including aneurysms, through introducing various crosslinking agents at the area of defect, and stimulating proliferation of endogenous cells, including stem cells at the site of the defect.

The patent discloses examples of how to repair such vascular defects, including providing data from a rabbit model.

View this patent on the USPTO website.