Cloning ungulates from a quiescent donor cell

Patent Number: 7,232,938

This is one of the original cloning patents from the inventor of Dolly the sheep :)

It covers a method of cloning an ungulate comprising:

(i) providing a quiescent ungulate cell as a diploid donor cell;

(ii) fusing the diploid donor cell to an enucleated oocyte recipient of the same species as the donor cell, thereby obtaining a reconstituted cell;

(iii) activating the oocyte recipient before, during or after fusion,

(iv) incubating the reconstituted cell such that an embryo develops, and

(v) transferring said embryo to a host female ungulate of the same species as the donor cell such that the embryo develops to term.

Animals covered in the patent include cows, goats, sheep and pigs, as well as the overall claim of "ungulates".

View this patent on the USPTO website.