Brain cell or nerve cell-protecting agents comprising medicinal ginseng

Patent Number: 7,235,267

Numerous people believe that natural remedies are not patentable. This is not correct.

In this specific patent, the use of ginsenoside Rb1 for acceleration of post CNS-infarct healing is covered. While numerous ginseng components have been known to have neuroprotective activities, this patent overcomes obviousness challenges by claiming only specific chemical structures and dosing regimes.

The mechanism of neuroprotection/acceleration of healing involved induction of neural stem cell cycling.

The patent provides numerous examples of efficacy, including improvement in the rat middle cerebral artery ligation model, as well as upregulation of bcl-2.

View this patent on the USPTO website.