Cationic liposome delivery of taxanes to angiogenic blood vessels

Patent Number: 7,238,369

Tumors are highly dependent on angiogenesis. The stem cell compartment is believed to supply circulating angioblasts which leave the bone marrow and home into tumors to support formation of new blood vessels.

This patent covers a unique method of specifically targeting chemotherapeutic taxanes to areas of angioblast mediated angiogenesis through the use of cationic lipids.

The patent is broader than most patents because in addition to claiming only killing of tumor associated neoangiogenic causing cells, it also covers the use of cationic lipids for delivery of proangiogneic agents.

This patent us ripe for commercialization since numerous products can be developed for either blocking or stimulating angiogenesis.

View this patent on the USPTO website.