This patent covers the use of neuroepithelial stem cells for treating brain damage. The claims specifically encompass conditionally immortalized cells and their administration into areas contra-lateral to the region where brain damage as occured.
The point the the cells have activity when administered in the contralateral region is very interesting. The patent specifically defines contralateral as "By "contra-lateral" it is intended that this refers to the hemisphere of the brain that does not contain the site of damage. Therefore, if there is an occlusion in the left hemisphere, then, obviously, the contra-lateral region is the right, undamaged, hemisphere".
One cell line covered is called "MHP36". The patent also covers the enhancement of activity of the administered cells through exercise and/or biofeedback methods.
View this patent on the USPTO website.
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