Methods of promoting osteogenesis
Patent Number: 7,268,139
Date of First Priority Issue: Thursday August 29th, 2002
Date Issued: Tuesday September 11th, 2007
Assignee: Scios, Inc. (Fremont, CA)
Inventors: Protter; Andrew A. (Palo Alto, CA), Liu; David Y. (Palo Alto, CA), O'Connor; Patrick (Farnwood, NJ)
From Class: Expansion
Comments: No comments
This patent covers the composition of matter for a small molecule inhibitor of p38 MAP kinase, as well as the use of these compounds for stimulation/acceleration of bone healing. Presumably since p38 is involved in inflammatory signaling, the inhibition of this pathway allows for regenerative activities to prevail, thus allowing healing unimpeded by inflammation. Indeed one of the claims does cover the inhibition of p38 MAP kinase as a method of decreasing activity of osteoclasts.
View this patent on the USPTO website.
Added to StemCellPatents.com on Sunday September 16th, 2007
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