This patent covers 2 main concepts. The first is acceleration of osteogenesis through administration of a bone morphogenic protein together with an inhibitor of TGF-beta. The claims also go on to cover a specific chemical entitiy that inhibits TGF-beta. The second main part of the patent is claim 3 in which the screening of compounds that inhibit TGF-beta and thereby promote BMP-induced osteogenesis is covered.
View this patent on the USPTO website.
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