Methods and compositions for modulating telomerase reverse transcriptase (TERT) expression
Patent Number: 7,279,328
Date of First Priority Issue: Monday September 30th, 2002
Date Issued: Tuesday October 9th, 2007
Assignee: Sierra Sciences, Inc. (Reno, NV)
Inventors: Andrews; William H. (Reno, NV), Foster; Christopher A. (Carmichael, CA), Fraser; Stephanie (Sparks, NV), Mohammadpour; Hamid (Reno, NV), Briggs; Laura (Reno, NV)
From Class: Expansion
Comments: No comments
This patent covers a screening system for assaying small molecule libraries for telomerase stimulating activity. Specifically, the inventors have found that telomerase reverse transcriptase (TERT) activity can be modulated by agents that alter the binding interaction of the GC-Box 5 repressor site with a repressor protein (or protein complex including the same). Using this system the inventors have set up a screening assay.
View this patent on the USPTO website.
Added to StemCellPatents.com on Sunday October 14th, 2007
Social & Bookmarking:
Add Comment
You must be signed-in to add your comments.
Sign-in now or Join the StemCellPatents.com Community for free.