Methods of creating constructs useful for introducing sequences into embryonic stem cells
Patent Number: 6942995
Date of First Priority Issue: Monday November 17th, 1997
Date Issued: Tuesday September 13th, 2005
Assignee: Deltagen, Inc. (San Carlos, CA)
Inventors: Klein, Robert D. (Palo Alto, CA); Brennan, Thomas J. (South San Francisco, CA)
From Class: Differentiation
Comments: No comments
This invention relates to the generation of knock-out animals Through genetically ablating a specific gene sequence in embryonic stem cells of an animal, it is possible to develop animals, called"knock-outs" which lack the specific sequences throughout all cells of the body. The patent has two independent claims directed towards unique gene-targeting constructs that through homologous recombination insert themselves in the place of the gene whose deletion is desired.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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