Oxpurine nucleosides and their congeners, and acyl, derivatives thereof, for improvement of hematopoiesis
Patent Number: 7,307,166
Date of First Priority Issue: Wednesday October 28th, 1987
Date Issued: Tuesday December 11th, 2007
Assignee: Wellstat Therapeutics Corporation (Gaithersburg, MD)
Inventors: von Borstel; Reid W. (Potomac, MD), Bamat; Michael K. (Potomac, MD), Hiltbrand; Bradley M. (Columbia, MD), Butler; James C. (Gaithersburg, MD), Shirali; Shyam (Gaithersburg, MD)
From Class: Expansion
Comments: No comments
This patent covers the composition of matter for several compounds and family of compounds that increase hematopoiesis. The compounds which are oxpurine nucleosides and their congeners, and acyl derivatives are demonstrated to accelerate hematopoietic reconstitution in both chemotherapy and irradiation induced suppression mouse models. In total the patent has over 70 examples.
The compounds in this patent will be interesting to examine in the stimulation of non-hematopoietic stem cells.
View this patent on the USPTO website.
Added to StemCellPatents.com on Saturday December 15th, 2007
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