Although the patent describes a keratinocyte population, the fact that the cells claimed can proliferate past the Hayflick limit, stimulated us to discuss this patent. The use of allogeneic cells for covering burns and other types of wounds has been widely known in the art, however in the current patent a type of keratinocyte with immense proliferative potential is described.
The patent covers the use of a keratinocyte population that is not immortalised and that may be replicated at least 150 times. These cells have been deposited with ATCC and are commercially available. The use of the cells for treatment of burn wounds and various types of ulcers is covered.
According to the specification the cells are derived from the epidermal part of a foreskin and are cultured according to standard methods of tissue culture such as in K/1 media.
View this patent on the USPTO website.
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