Connective tissue substitutes, method of preparation and uses thereof

Patent Number: 7,335,230

One of the areas in which regenerative medicine has caused the most advancement is in repair of connective tissue injuries. The current patent addresses this area. Specifically, the patent covers an object that can be implanted and used as a substitute for a connective tissue.

The objected is made with a pair of bone anchors, with at least one filament connecting the bone achors at their proximal ends and at least one matrix layer coating the support filament. The support filament is made in such a manner that it can be colonized by cells.

The implant obviously may be precoated with growth factors or chemokines to increase the rate of cellular colonization, or may actually be precolonized in vitro prior to administration.

View this patent on the USPTO website.