Methods of treatment of hematopoietic disorders

Patent Number: 7,347,999

This patent covers a "method of treating a mammal suffering from a hematopoietic disorder wherein bone marrow transplantation is required" through the administration of bone marrow cells and a bone matrix.  The patent is interesting since it covers into only administration into the bone but also in sites outside of the bone.  The patent covers various additives that can be used to stimulate the hematopoietic activity of the stem cells in the graft.

The importance of the three dimensional structure of the bone marrow is highlighted by this patent.  Other studies have demonstrated that simply injection of the bone marrow stem cells directly into the bone marrow of the recipient has substantially better hematopoietic recovery effects as compared to intravenous administration.

View this patent on the USPTO website.