Patents (1436 Stem Cell Patents)

Placental growth factor as a target for the treatment of osteoporosis

Patent Number: 7,357,929

Date of First Priority Issue: Friday June 28th, 2002
Date Issued: Tuesday April 15th, 2008
Assignee: D. Collen Research Foundation VZW (Leuven, BE)
Inventors: Carmeliet; Peter (Blanden, BE), Collen; Desire (Winksele, BE), Bouillon; Roger (Winksele, BE), Carmeliet; Gertrudis (Blanden, BE)

From Class: Use

This patent covers the inhibition of placental growth factor as a method of treating osteoporosis.  The one issued claim is restricted to inhibition of placental growth factor using an antibody or fragments of the antibody.

The inventor demonstrated inhibition of bone resorption in an animal model, as well as in vitro using anti-placental growth factor antibodies. Interestingly in the examples the use of mesenchymal stem cells together with this antibody are also described. 

 

View this patent on the USPTO website.

Added to StemCellPatents.com on Sunday April 20th, 2008

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1 Comment | Add Comment

Christineball33 said...

Created 2008-04-24 11:55:20 EST
I dont believe this ! one woulld think that placental growth factor would be useful in the treatment of osteoporosis by means of activating osteoblasts, no?  This patent seems to be teaching that placental growth factor should be inhibited.
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