This patent covers methods of growing embryonic stem cells outside of the body using novel tissue culture media and media additives.
Specifically, it covers the use of compounds that inhibit MEK-1 and/or MEK-2, as well as compounds that activate gp130 for use in stem cell propagation. This claim conceptually blocks anyone from using compounds known and unknown that modulate these pathways for use in stem cell propagation ex vivo.
The patent also provides examples compounds that may be used.
View this patent on the USPTO website.
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