Cellular therapy to heal vascular tissue

Patent Number: 7,387,645

The current patent covers methods of treating/repairing aneurysms through autologous cells, including stem cells by delivering the cells into an aneurysmal site so as to repair the blood vessel.  Types of cells useful for practising the invention include bone marrow stem cells, adipose derived stem cells and blood derived stem cells.  Addition of various extracellular matrix components is also provided to increase the strength of the regenerating blood vessel.

Since aneurysms are associated with matrix metalloprotease secretion it is interesting that stem cells, many of which actually express matrix metalloproteases, are actually helpful for this condition.

View this patent on the USPTO website.