The current patent covers a cosmetic generated using a variant of stromal derived factor (SDF-1) which the inventors termed stem cell active factor (SCAF). The natural function of SDF-1 is to call in stem cells to injured tissue, for example, after a heart attack there is a surge of SDF-1 which is involved in mediating mobilization of stem cells from the bone marrow and causing them to home to the injured heart muscle in an attempt to heal it. SDF-1 is also produced at a basal level by the bone marrow and is one of the reasons why recipients of bone marrow transplants can recieve intravenous injections of the donor bone marrow (the SDF-1 in the recipient bone marrow induces homing of the intravenously injected donor cells to go to the recipient bone marrow).
In addition to claiming the SCAF together with a cosmetically acceptable carrier, the inventors also cover a plethora of plant and herbal extracts.
View this patent on the USPTO website.
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jonnyboy said...
If you make cosmetics out of SDF-1, you may as well try other stem cell modulating agents such as VEGF...perhaps even better would be topical inhibitors of the HDACs...paint your face with resveratrol ! I bet Sirtris must have this covered though.