Feeder-free culture method for embryonic stem cells or primate primordial stem cells
Patent Number: 7,413,902
Date of First Priority Issue: Thursday October 23rd, 1997
Date Issued: Tuesday August 19th, 2008
Assignee: Geron Corporation (Menlo Park, CA)
Inventors: Bodnar; Andrea G. (Oshawa, CA), Chiu; Choy-Pik (Cupertino, CA), Gold; Joseph D. (San Francisco, CA), Inokuma; Margaret (San Jose, CA), Murai; James T. (San Bruno, CA), West; Michael D. (Boston, MA)
From Class: Expansion
Comments: No comments
This patent covers the expansion of embryonic stem cells (referred to in the patent as primate primordial stem cells) by growing them in a media that lacks feeder cells but has the extracellular matrix of lysed fibroblast cells. It also covers growth of embryonic stem cells in extracellular matrix combined with agents such as FGF, forskolin, and various nutrients. The point of the patent is that the embryonic stem cells that are grown do not diffentiate while they are expanding. Geron has some other similar patents in the area of growing stem cells without the need for feeder cells.
View this patent on the USPTO website.
Added to StemCellPatents.com on Sunday August 24th, 2008
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