Compounds modulating c-kit activity
Patent Number: 7,498,342
Date of First Priority Issue: Thursday June 17th, 2004
Date Issued: Tuesday March 3rd, 2009
Assignee: Plexxikon, Inc. (Berkeley, CA)
Inventors: Ibrahim; Prabha N. (Mountain View, CA), Hurt; Clarence R. (San Ramon, CA), Zhang; Chao (Moraga, CA), Zhang; Jiazhong (Oakland, CA)
From Class: Expansion
Comments: No comments
c-kit is involved in hematopoietic stem cell self-renewal, however it is also found in other stem cells as well. For example, cardiac stem cells express c-kit. This is an exciting drug target and other companies have patents covering its inhibitors, for example, #7,211,600 by Sugen.
The current patent covers composition of matter for various chemical entities that are capable of modulatin c-kit activity.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday March 9th, 2009
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