Intramyocardial injection of autologous bone marrow

Patent Number: 7097832

This patent is useful for the induction of collateral blood vessel formation (for example angiogenesis) in ischemic tissue. There are numerous conditions that may benefit from induction of said collateral blood vessel formation. For example ischemia of the various organs may be treated using this patent. The patent overall teaches the use of autologous bone marrow cells, either ex vivo cultured, or freshly isolated, for induction of collateral blood vessel formation. There is one independent claim in the patent, which covers ALL bone marrow cells, without restricting itself. Dependent claims cover numerous different modifications that may be made to the bone marrow in order to increase angiogenic potential. The collateral blood vessel formation by bone marrow cells seems to be restricted only to autologous use.

View this patent on the USPTO website.