Inhibitors of proteasomal activity for stimulating hair growth
Patent Number: 6884769
Date of First Priority Issue: Friday July 10th, 1998
Date Issued: Tuesday April 26th, 2005
Assignee: OsteoScreen, Inc. (San Antonio, TX
Inventors: Mundy, Gregory R. (San Antonio, TX); Garrett, I. Ross (San Antonio, TX); Rossini, Jorge Gianny (San Antonio, TX) )
From Class: Expansion
Comments: No comments
Proteosomes are becoming important biological targets in drug discovery. For example pathways associated with numerous diseases, such as NF-kB are dependent on proteosomal activation. In the case of NF-kB the proteosomal degradation of phosphorylated IKB is what allows translocation of NF-kB into the nucleus.
In this patent inhibition of the chymotrypsin-like activity proteasomes is claimed as a method of enhancing bone growth and formation.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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