Cationic lipid compositions targeting angiogenic endothelial cells

Patent Number: 7094424

This patent teaches ways of selectively targeting a compound to endothelial cells. This could be used to administer stem cell stimulators in order to increase angiogenesis. The patent has one independent claim,that is "A method for selectively labeling angiogenic endothelial cells in vivo, the method comprising administering to a mammal a liposomal complex comprising cationic lipids and a detectable label wherein the complex has greater affinity for angiogenic endothelial cells as compared to corresponding normal endothelial cells; and allowing the liposomal complex to selectively associate with angiogenic endothelial cells of an angiogenic blood vessel for a time and in a manner such that the angiogenic endothelial cells are detectably labeled. "

View this patent on the USPTO website.