Cultures of GFAP+ nestin+ cells that differentiate to neurons
Patent Number: 6878543
Date of First Priority Issue: Monday October 25th, 1999
Date Issued: Tuesday April 12th, 2005
Assignee: NsGene SA (Ballerup, DK)
Inventors: Wahlberg, Lars (Asnaes, DK); Campbell, Kenneth (Cincinnati, OH); Skogh, Charlotta (Malmo, SE); Eriksson, Cecilia (Falsterbo, SE); Wictorin, Klas (Lund, SE)
From Class: Differentiation
Comments: No comments
Generation and expansion of neuronal cells is described in this patent through inducting proliferation of GFAP+, nestin+ stem cells of neuronal origin through treatment with EGF, amphiregulin, aFGF, bFGF, TGF.alpha. and then inducing differentiation through serum free culture.
The cells generated by this means can be made into neurons or glial cells depending on culture conditions.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
Social & Bookmarking:
Add Comment
You must be signed-in to add your comments.
Sign-in now or Join the StemCellPatents.com Community for free.