Mixed chimerism and tolerance
Patent Number: 6877514
Date of First Priority Issue: Thursday May 9th, 1996
Date Issued: Tuesday April 12th, 2005
Assignee: The General Hospital Corporation (Boston, MA)
Inventor: Sykes, Megan (Charlestown, MA)
From Class: Use
Comments: No comments
This patent teaches how to induce allogeneic tolerance to transplanted grafts through making the recipient a chimera in terms of blood composition. In other words, donor hematopoietic stem cells are administered in order to make the recipient have both donor blood cells circulating, as well as some left over recipient cells.
This system has been shown effective in several animal models.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
Social & Bookmarking:
Add Comment
You must be signed-in to add your comments.
Sign-in now or Join the StemCellPatents.com Community for free.