This patent provides methods and vectors for transfection of embryonic stem cells. This patent is useful for generation of various animal research models that have a genetic modification introduced into the whole animal. Additionally, transfection of embryonic stem cells could be useful for a variety of different things, including using the embryonic stem cells as a vector...or in another way...the embryonic stem cells can be transfected with a suicide gene.
View this patent on the USPTO website.
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