Combinations and methods for promoting in vivo liver cell proliferation and enhancing in vivo liver-directed gene transduction
Patent Number: 6790838
Date of First Priority Issue: Tuesday February 23rd, 1999
Date Issued: Tuesday September 14th, 2004
Assignee: Amgen, Inc. (Thousand Oaks, CA); Imperial College Innovations LTD (London, GB)
Inventors: Alison, Malcolm R. (London, GB); Coutelle, Charles (London, GB); Forbes, Stuart J. (London, GB); Hodgson, Humphrey J. F. (London, GB); Sarosi, Ildiko (Newbury Park, CA); Themis, Michael (Oxfordshire, GB)
From Class: Expansion
Comments: No comments
This patent teaches ways of improving the transfection of liver cells with genes in vivo. Transfection of liver cells is performed through the administration of the thyroid hormone T3, as well as keratinocyte growth factor. The transfection of liver cells may be performed not only for treatment of genetic disorders, but also for induction of islet differentiation.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
Social & Bookmarking:
Add Comment
You must be signed-in to add your comments.
Sign-in now or Join the StemCellPatents.com Community for free.