Use of delta-like protein to inhibit the differentiation of stem cells
Patent Number: 6613565
Date of First Priority Issue: Friday March 1st, 1996
Date Issued: Tuesday September 2nd, 2003
Assignee: ImClone Systems Incorporated (New York, NY); Trustees of Princeton University (Princeton, NJ)
Inventors: Witte, Larry (Stormville, NY); Pytowski, Bronislaw (New York, NY); Moore, Kateri A. (Princeton, NJ); Lemischka, Ihor R. (Princeton, NJ)
From Class: Differentiation
Comments: No comments
This patent covers the inhibition of hematopoietic stem cell differentiation through administration of the protein called "delta-like protein" (dlk).
The patent teaches not only the use for expansion, but also for protecting the stem cell compartment from the effects of chemotherapy or radiotherapy.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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