I-Sce I induced gene replacement and gene conversion in embryonic stem cells
Patent Number: 6566579
Date of First Priority Issue: Thursday April 18th, 1996
Date Issued: Tuesday May 20th, 2003
Assignee: Institut Pasteur (Paris, FR); Institut Curie (Paris, FR); Centre Nationale de la Recherche Scientifique (Paris, FR)
Inventors: Jaisser, Frederic (Malakoff, FR); Cohen-Tannoudji, Michel (Paris, FR); Robine, Sylvie (Vanves, FR); Choulika, Andre (Paris, FR); Louvard, Daniel (Sceaux, FR); Babinet, Charles (Paris, FR)
This patent teaches ways of generating knockout mice through a new targeting vector. Alternatively, knockout human embryonic stem cells can be made by this approach for generation of new tissues.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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