Low molecular weight cell, bone marrow and immune stimulants
Patent Number: 6498150
Date of First Priority Issue: Tuesday October 17th, 1995
Date Issued: Tuesday December 24th, 2002
Assignee: Dovetail Technologies, Inc. (College Park, MD)
Inventors: Taub, Floyd (Silver Spring, MD); Perun, Thomas J. (Round Lake, IL); Murray, Christopher K. (Longmont, CO); Daughenbaugh, Randall J. (Longmont, CO); Lednicer, Daniel (Rockville, MD)
From Class: Expansion
Comments: No comments
This patent covers the composition of matter for several aminocarboxylic acid amide derivatives that are both immunostimulatory, as well as augment hematopoietic activity of stem cells. This seems very interesting a combination since many cytokines that stimulate the immune system, at least the Th1 arm of the immune system, are also suppressive to the hematopoietic compartment.
For example, interferon gamma is a potent Th1 cytokine but causes myelosuppression when expressed locally.
This patent is definatly worth while for entry into clinical development.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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