Methods for use of Mpl ligands with primitive human stem cells
Patent Number: 6326205
Date of First Priority Issue: Monday October 30th, 1995
Date Issued: Tuesday December 4th, 2001
Assignee: Systemix, Inc. (Palo Alto, CA)
Inventors: Murray, Lesley J. (San Jose, CA); Young, Judy C. (San Carlos, CA)
From Class: Expansion
Comments: No comments
Thrombopoietin (TPO) is a stimulatory molecule for early hematopoietic stem cells. In this patent the use of TPO and other ligands of its receptor, called mpl, are disclosed for purposes of expansion, and/or megakaryocytic differentiation of hematopoietic stem cells.
It would be interesting to see if other types of stem cells also respond to mpl ligands in the manner that hematopoietic stem cells do.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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