Use of c-kit ligand with TNF-.alpha. and hematopoietic factors for the expansion or differentiation of hematopoietic cells
Patent Number: 6159461
Date of First Priority Issue: Thursday April 23rd, 1992
Date Issued: Tuesday December 12th, 2000
Assignee: Sloan-Kettering Institute for Cancer Research (New York, NY)
Inventors: Besmer, Peter (New York, NY); Buck, Jochen (New York, NY); Moore, Malcolm A. S. (New York, NY); Nocka, Karl (Harvard, MA)
From Class: Expansion
Comments: No comments
Combinations of cytokines are provided in this patent for expanding the number of hematopoietic stem cells. Cytokines include stem cell factor, tnf-alpha, and pixy. This is somewhat interesting since TNF alpha is usually considered to inhibit hematopoiesis.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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