Patents (1436 Stem Cell Patents)

Expansion of bone marrow stromal cells

Patent Number: 5962323

Date of First Priority Issue: Friday December 29th, 1995
Date Issued: Sunday September 5th, 1999
Assignee: ALG Company (Marlboro, MA)
Inventors: Greenberger, Joel S. (Sewickley, PA); Hurwitz, David R. (Acton, MA)

From Class: Expansion
Comments: No comments

This patent teaches how to grow bone marrow stromal cells in vitro. Several types of culture conditions for growing stromal cells are given. For example, the stromal cells may be expanded by treatment with FGF-1 on gelatin-coated plates. If FGF-1 can stimulate stromal cells in vitro, one wonders whether it also has similar in vivo abilities. The reason this is important is that there are currently ongoing clinical trials that used FGF-1 for induction of angiogenesis both for the heart as well as limb ischemia.

View this patent on the USPTO website.

Added to StemCellPatents.com on Monday October 16th, 2006

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