Application of shear flow stress to chondrocytes or chondrocyte stem cells to produce cartilage
Patent Number: 5928945
Date of First Priority Issue: Wednesday November 20th, 1996
Date Issued: Tuesday July 27th, 1999
Assignee: Advanced Tissue Sciences, Inc. (La Jolla, CA)
Inventors: Seliktar, Dror (Atlanta, GA); Dunkelman, Noushin (San Diego, CA); Peterson, Alvin Edward (Jamul, CA); Schreiber, Ronda Elizabeth (Ramona, CA); Willoughby, Jane (Del Mar, CA); Naughton, Gail K. (Del Mar, CA)
This patent teaches how to generate cartilage through the growth of chondrocyte stem cells under shear stress. It is believed that the sheer stress activates certain mechanoreceptors which cause appropriate differentiation of the chondrocyte stem cells into cartilage.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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