Synergistic composition and methods for treating neoplastic or cancerous growths and for restoring or boosting hematopoiesis

Patent Number: 6998125

Despite its title, the patent doesn't really deal with stimulation of hematopoiesis. It covers a method of immunizing a cancer pateint with tumor antigens and concurrenly inhibiting TGF-beta. It is known that TGF-beta is an immunosuppressive agent released by cancer cells. It may be that since TGF-b inhibits hematopoiesis, the inhibition of TGF-b would not only derepress the immune system in a cancer pateint but would also stimulate hematopoiesis. This of course poses the interesting question if cancer patients actually have decreased hematopoiesis due to TGF beta. This may be possible since cancer patients are known to be anemic. In any case, the patent has 1 independent claim which covers a method of treating cancer through essentially immunization combined with TGF beta inhibition.

View this patent on the USPTO website.