Protection of hemopoietic cells
Patent Number: 5739110
Date of First Priority Issue: Monday September 12th, 1994
Date Issued: Tuesday April 14th, 1998
Assignee: Biomeasure Inc. (Milford, MA); Societe de Conseils de Recherches Et D'Applications Scientifiques (FR)
Inventors: Bogden, Arthur E. (West Yarmouth, MA); De Paillette, Evelyn Deschamps (Paris, FR)
From Class: Expansion
Comments: No comments
This patent covers the use of the peptide AcSDKP for inhibiting hematopoietic stem cell proliferation and protecting the stem cells from radiation or chemotherapy. In addition, since the angiotensin-converting enzyme is responsible for degradation of AcSDKP, inhibition of ACE by clinically used inhibitors for the inhibition of hematopoiesis is provided. ACE inhibitors include captopril, fentiapril, pivalpril, zefenopril, ano-alacepril, enalapril, lisinopril, benzepril, indolapril, pentopril, indalapril, cliazapril, and fusinopril.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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