Stroma-derived proteoglycan containing composition which promotes differentiation and maintains the self-renewal capacity of long-term bone marrow culture-initiating cells
Patent Number: 5523286
Date of First Priority Issue: Friday November 12th, 1993
Date Issued: Tuesday June 4th, 1996
Assignee: Regents of the University of Minnesota (Minneapolis, MN)
Inventors: McGlave, Philip B. (St. Paul, MN); Verfaillie, Catherine M. (St. Paul, MN)
From Class: Expansion
Comments: No comments
This patent provides a proteoglycan matrix that can be used for growth and expansion of hematopoietic stem cells. Interestingly this patent promotes not just growth of CD34+ hematopoietic stem cells, but specifically, hematopoietic stem cells that are capable of supporting long term cultures.
This patent can be used for expanding hematopoietic stem cells for autologous bone marrow transplant, or may be useful for expanding cord blood stem cells for adult donors.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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