Peptide compounds which inhibit the proliferation of epidermal or epithelial stem cells

Patent Number: 5484770

This patent discloses peptides that specifically inhibit proliferation of epidermal and/or epithelial stem cells. On the one hand this patent is useful for protection of such stem cells when the patient is treated with a cytotoxic agent that targets proliferating cells, such as in the case of cancer therapy. On the other hand, this patent may be used in combination with other patents or technologies so as to stop stem cell proliferation, but to induce differentiation or other activities on stem cells that do not occur when the cell is actively proliferating.

On additional use of this patent is during the transfection of cells with agents that transfect only non-proliferating cells.

View this patent on the USPTO website.