Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells
Patent Number: 5437994
Date of First Priority Issue: Thursday June 15th, 1989
Date Issued: Tuesday August 1st, 1995
Assignee: Regents of The University of Michigan (Ann Arbor, MI)
Inventors: Emerson, Stephen G. (Ann Arbor, MI); Clarke, Michael F. (Ann Arbor, MI); Palsson, Bernhard O. (Ann Arbor, MI)
This patent teaches methods of expanding human hematopoietic cells ex vivo using various cytokine cocktails. The patent is heavily cited by other patents and its claims appear to be far-reaching.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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