SCL: a hematopoietic growth and differentiation factor
Patent Number: 5214133
Date of First Priority Issue: Friday November 17th, 1989
Date Issued: Tuesday May 25th, 1993
Assignee: The United States of America as represented by the Secretary of the (Washington, DC)
Inventors: Kirsch, Ilan R. (Potomac, MD); Begley, C. Glenn (North Carlton, AU)
From Class: Expansion
Comments: No comments
This patent is for a transcription factor associated with stem cell activity. The factor is a basic helix-loop-helix transcription factor called SCL/Tal1.
It is expressed in cells that possess hematopoietic stem cell activity and controls numerous genes associated with stem cell functions.
Modification of activity of this transcription factor may be used theoretically for manipulation of stem cell differentiation, expansion, or survival.
View this patent on the USPTO website.
Added to StemCellPatents.com on Monday October 16th, 2006
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