Category: Embryonic (11)

Ability of ES Cells to De-differentiated and Reprogram Other Cells is Augmented by Nanog Overexpression in ES Cells

Edinburgh, UK - Dr. Austin Smith’s group reported the ability of embryonic stem cells to reprogram somatic cells is markedly augmented by overexpression of the Nanog transcription factor in the embryonic stem cell (Silva J et al. Nanog promotes transfer of pluripotency after cell fusion. Nature. 2006 Jun 22;441(7096):997-1001). These findings are of great importance...