Category: Use (79)
Mesenchymal Stem Cells Augmented by Estrogen
Indianapolis, Indiana -
Mesenchymal stem cells, have very potent therapeutic potential because they can be used in an allogeneic manner, they can differentiate into many new types of tissue, and they produce numerous growth factors. Mesenchymal stem cells have been demonstrated in non-clinical systems to be effect in
Duchenne Muscular Dystrophy Calls Stem Cells
Milan, Italy -
Duchenne Muscular Dystrophy is a lethal genetic condition, characterized by progressive muscle weakness caused by mutations in the dystrophin gene. Approaches to treatment of this condition have included the use of cord blood stem cells, however little functional improvement is seen, even in animal models. US patent 
2 Comments
Mesenchymal stem cells made into nucleus pulposus cells
Lumbar disc degeneration is a significant cause of morbidity. Given that the key cells maintaining the mass of the disc are nucleus pulposus cells, one of the aims in regenerative medicine has been to treat disc degeneration by administration of stem cells.
However, one major question arises, would it be more beneficial to administer stem...
Treating back pain with mesenchymal stem cells
Pittsburgh, Pennsylvania -
Vertebral disc degeneration is a major cause of suffering internationally. Although various interventions exist, such as disc replacement and surgical fusion, these have numerous long-term limitations such as need for resurgery, degeneration of the adjacent disc, and relapse of pain. One exciting method of treating...
1 Comment
Mesenchymals for wound healing
Nara Medical University, Japan - Mesenchymal stem cells are classically defined as CD34 negative, CD45 negative, SH2 and SH4 positive, and Thy-1 (CD90) positive cells. Therapeutically mesenchymal stem cells are attractive because they do not require matching with recipients, supposedly...
1 Comment
Breast cancer FGF-2 and VEGF calls in mesenchymal stem cells
Augusta, Georgia - It is believed by many that tissue resident stem cells subsequent to accumulating DNA damage lose proliferative controls and transform into tumors. For example, there is a classical study in which mice were infected with h.pylori and gastric cancer was allowed to develop. Strikingly, the gastric cancer was derived from bone marrow stem cells...
Velcade guides stem cells to bone
Boston, Massachusetts - Stem cell therapeutics are difficult to commercialize because of the need for cellular manipulation. Even business models that involve off the shelf universal stem cells have the issue that you need are selling an actual biologic product, a product that is very difficult to standardize and ensure quality...
2 Comments
Stem Cells in Davos
[Watch the Video] Youtube made a video contest for best "new ideas" to change the world in 2008. The winning videos will be presented at the World Economic Forum at Davos. The idea here is that the world will be a better place if therapeutic implimentation of autologous bone marrow stem cells are supported by governments and businesses !! If you like the video please pass on to...
Mobilized Stem Cells for Peripheral Artery Disease
Hangzhou, China -
The use of autologous bone marrow stem cells for peripheral artery disease is occuring in the US as part of clinical trials. The rational is that insertion of stem cells into ischemic muscle leads to angiogenesis either through the endothelial precursor... Erlangen, Germany -
Although mesenchymal stem cells are primarily known for their differentiation abilities, the first clinical trials, and most likely BLA grantings, will be for immune modulation by these cells in the conditions of graft versus host disease and Crohn's disease.
In the same way that
T regulatory cell control of bone resorption