Human stem cells and monoclonal antibodies

Patent Number: 5035994

This patent futher strengthens Civin's claim (no pun intended) on the hematopoietic stem cell. The first independent claim covers "A method of isolating a population of human cells containing pluripotent lympho-hematopoletic stem cells" through ANY ANTIBODY that bind to the antigen that is recognized by the antibody deposited with ATCC under Accession No. HB-8483. The second independent claim also covers "A method of isolating a population of human cells containing pluripotent lympho-hematopoietic stem cells " although this time the inventor provides a specific means of isolation, that is, through the use of a solid surface for binding the antibody so that the cells of interest bind to the solid surface.

View this patent on the USPTO website.