Soft tissue and bone augmentation and bulking utilizing muscle-derived progenito compositions, and treatments thereof

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This patent covers the extraction and use of a muscle derived stem cell that is positive for the markers desmin, CD34, flk-1 and M-Cadherin, but does not express the hematopoietic marker CD45 nor c-kit.

This cell type is useful for treatment of a variety of disorders associated with muscle degeneration. Although the inventors state that the cell is different than mesenchymal stem cells, in part because their cell expresses CD34 and mesenchymal stem cells do not, circulating mesenchymal cells of US patent #5846796 actually do express CD34 !

I wonder whether the cells of the current invention, similar to mesenchymal stem cells, can be transplanted across allogeneic barriers without the need for immune suppression?

View this patent on the USPTO website.