Compositions for identification and isolation of stem cells

Patent Number: 7,223,549

This patent covers several antibodies that specifically bind ectodermally-derived stem cell but have weaker affinity for stem cells of mesodermal and endodermal origin. The antibodies seem to bind prostate and liver stem cells but not dermal stem cells.

The antibodies are deposited with ATTC and are commercially available.

Unfortunately, the ligand for the antibodies was not disclosed.

This patent is useful not only for isolation of stem cells but potentially for seeking cancer stem cells for identification of cancer stem cell antigens useful for cancer vaccine development.

View this patent on the USPTO website.