Patents (1436 Stem Cell Patents)

Insulin-secreting immortalized liver cell line modified by glucose sensitivity

Patent Number: 7,312,077

Date of First Priority Issue: Wednesday October 2nd, 2002
Date Issued: Tuesday December 25th, 2007
Assignee: Unknown Assignee(s)
Inventors: Kobayashi; Naoya (Okayama-shi, Okayama, JP), Tanaka; Noriaki (Asakuchi-gun, Okayama, JP), Okitsu; Teru (Okayama-shi, Okayama, JP), Yoon; Ji-Won (Calgary, Alberta, CA), Jun; Hee-Sook (Calgary, Alberta, CA), Shin; Seungjin (Calgary, Alberta, CA)

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It has previously been demonstrated that rat hepatic cells can be coaxed into producing insulin by isolating the hepatic cells from an animal that was first primed with a hepatoxin, and subsequently exposing the isolated hepatic cells to high glucose concentrations.

In the current patent a hepatic cell line that has been immortalized, called FERM BP-7498 is patented. The claims are only limited to the cell that has been deposited with ATCC.

View this patent on the USPTO website.

Added to StemCellPatents.com on Monday December 31st, 2007

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