Patents (1436 Stem Cell Patents)

Compounds to promote regeneration of bone marrow

Patent Number: 7,423,029

Date of First Priority Issue: Friday March 23rd, 2007
Date Issued: Tuesday September 9th, 2008
Assignee: Zoltan Laboratories, LLC (Austin, MN)
Inventors: Kiss; Zoltan (Austin, MN)

From Class: Expansion
Comments: No comments

This patent covers the use of heterocyclic trialkyl ammonium-containing compounds for stimulation of bone marrow proliferation and differentiation after myeloablation or other insults to the hematopoietic stem cell compartment.  The toxicity profile of the compounds appears favorable.

Data in the examples section demonstrates protection from cyclophosphamide destruction of the bone marrow, as well as radiation and several other models.

Other stimulators of hematopoiesis include acyl deoxyribonucleosides, polyamines, and immune stimulatory peptides.

View this patent on the USPTO website.

Added to StemCellPatents.com on Sunday September 14th, 2008

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