Enriched preparation of human fetal multipotential neural stem cells

Patent Number: 7,468,277

This patent essentially covers a composition of purified human fetal multipotent neural stem cells that are isolated extracted directly from the brain of a human fetus without initial epidermal growth factor expansion.  Specifically, the wherein the enriched preparation is capable of: (1) generating neurons, astrocytes, and oligodendrocytes and (2) being propagated for at least 7 weeks, and wherein the enriched preparation comprises a transcriptionally active nestin enhancer or musashi promoter.

The cells may be purified from the hippocampus or ventricular zone of the fetal brain. 

This patent reminds us of some of the patents held by StemCells Inc using fetal brain progenitors that have been purified by CD133 selection such as #7,153,686. 

View this patent on the USPTO website.