This patent covers methods of producing tooth progenitor cells from either neural stem cells or embryonic stem cells. The process covers contacting the stem cell with cells derived from the oral epithelium so as to induce expression of the genes Barx-1 and Dlx-5.
Essentially this patent is teaching markers associated with the process of differentiation, as well as progenitor associated markers such as Msx-1, Lhx-7 and Pax-9.
Other patents have covers stem cells collected from teeth, however this one seems to be unique in that it is actually covering a method of making the tooth progenitor cell.
View this patent on the USPTO website.
You must be signed-in to add your comments.
Sign-in now or Join the StemCellPatents.com Community for free.